A unique chemical has recently been shown to be effective in treating brain tumors, according to a Nobel Prize-winning Turkish chemist.
The EdU molecule has been one of the most commonly utilized molecules in molecular biology since 2008, according to Aziz Sancar, whose study was published in the Proceedings of the National Academy of Sciences on Tuesday.
Sancar, who was born in Turkey but has spent the majority of his life living and working in the US, said: “I worked for 10 years on the DNA mechanism, which got me the Nobel Prize.
According to him, scientists began studying the EdU molecule in January and found out it destroys cells in February.
He stated, “We have verified that it is certain and done all the checks.
The study concluded that EdU is a “promising option for treating malignancies of the brain” due to its capacity to pass the blood-brain barrier.
The majority of medications are unable to go from the blood to the brain. For instance, because this barrier prevents the medication cisplatin, which is used to treat cancer patients, from passing through, brain tumors cannot be treated with it. This EdU enters the brain without difficulty and effortlessly, he claimed.
Study using mice
Prior to being tried on humans, the discovery will first be tested on mice. According to Sancar, the mouse tests would last two years.
According to Sancar, who spoke to cancer patients, the success rate of discovery in human treatment is currently 3 percent.
“Be hopeful and do the best you can with the opportunities that are available right now,” I say.
Sancar, along with Tomas Lindahl and Paul Modrich, received the 2015 Nobel Prize in Chemistry for their mechanistic research on DNA repair. Sancar was born in the region of Mardin in southeast Turkey.
